CLEFMA
Catalog No: 615201
CAS Number: 1246964-32-8
Purity: 98% Min.
CLEFMA has anti-proliferative activity in H441 cells. CLEFMA may induce autophagic cell death that was inhibited by specific autophagy inhibitor 3-methyladenine. The results suggest that the potent and novel curcuminoid, CLEFMA, offers an alternative mode of cell death in apoptosis-resistant cancers.
CLEFMA, Bulk in stock, contact us by email for the Bulk quotation.
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Chemical Information
| Name | CLEFMA |
|---|---|
| Iupac Chemical Name | (2z)-4-[(3E,5e)-3,5-bis[(2-chlorophenyl)methylene]-4-oxo-1-piperidinyl]-4-oxo-2-butenoic acid |
| Synonyms | CLEFMA |
| Molecular Formula | C23H17Cl2NO4 |
| Molecular Weight | 442.29 |
| Smile | ClC1=C(C=CC=C1)\C=C\1/CN(C\C(\C1=O)=C/C1=C(C=CC=C1)Cl)C(\C=C/C(=O)O)=O |
| InChiKey | ABOUDPJRQGWQNW-GGDLZHBGSA-N |
| InChi | InChI=1S/C23H17Cl2NO4/c24-19-7-3-1-5-15(19)11-17-13-26(21(27)9-10-22(28)29)14-18(23(17)30)12-16-6-2-4-8-20(16)25/h1-12H,13-14H2,(H,28,29)/b10-9-,17-11+,18-12+ |
| CAS Number | 1246964-32-8 |
| Related CAS | 1246964-32-8 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Yellow Solid |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years) |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
