COTI-2 is an P53 gene modulator and AKT2 inhibitor. OTI-2 is active against multiple human cancer cell lines in vitro and in vivo.
For research use only. We do not sell to patients.
Name | COTI-2 |
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Iupac Chemical Name | (E)-N'-(6,7-dihydroquinolin-8(5H)-ylidene)-4-(pyridin-2-yl)piperazine-1-carbothiohydrazide |
Synonyms | COTI-2; COTI2; COTI 2 |
Molecular Formula | C19H22N6S |
Molecular Weight | 366.48 |
Smile | S=C(N1CCN(C2=NC=CC=C2)CC1)N/N=C3CCCC4=C\3N=CC=C4 |
InChiKey | UTDAKQMBNSHJJB-CJLVFECKSA-N |
InChi | InChI=1S/C19H22N6S/c26-19(23-22-16-7-3-5-15-6-4-10-21-18(15)16)25-13-11-24(12-14-25)17-8-1-2-9-20-17/h1-2,4,6,8-10H,3,5,7,11-14H2,(H,23,26)/b22-16+ |
CAS Number | 1039455-84-9 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
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Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |