CRT0273750
Catalog No: 20258
CAS Number: 1979939-16-6
Purity: ≧98.0%
CRT0273750 modulates LPA levels in plasma and is suitable for in vivo studies.
For research use only. We do not sell to patients.
Chemical Information
| Name | CRT0273750 |
|---|---|
| Iupac Chemical Name | (S)-N-(1-(4-chlorophenyl)ethyl)-3-(3-(4-(trifluoromethoxy)benzyl)-3H-imidazo[4,5-b]pyridin-2-yl)propanamide |
| Synonyms | CRT0273750 ; CRT 0273750 ; CRT-0273750 |
| Molecular Formula | C25H22ClF3N4O2 |
| Molecular Weight | 502.92 |
| Smile | FC(F)(F)OC1=CC=C(CN2C(CCC(N[C@@H](C)C3=CC=C(C=C3)Cl)=O)=NC4=CC=CN=C42)C=C1 |
| InChiKey | HXYXHSDYBDFOFO-INIZCTEOSA-N |
| InChi | InChI=1S/C25H22ClF3N4O2/c1-16(18-6-8-19(26)9-7-18)31-23(34)13-12-22-32-21-3-2-14-30-24(21)33(22)15-17-4-10-20(11-5-17)35-25(27,28)29/h2-11,14,16H,12-13,15H2,1H3,(H,31,34)/t16-/m0/s1 |
| CAS Number | 1979939-16-6 |
| Related CAS | 1979939-16-6 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white Solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1: Shah P, Cheasty A, Foxton C, Raynham T, Farooq M, Gutierrez IF, Lejeune A, Pritchard M, Turnbull A, Pang L, Owen P, Boyd S, Stowell A, Jordan A, Hamilton NM, Hitchin JR, Stockley M, MacDonald E, Quesada MJ, Trivier E, Skeete J, Ovaa H, Moolenaar WH, Ryder H.
Discovery of potent inhibitors of the lysophospholipase autotaxin. Bioorg Med Chem Lett. 2016 Nov 15;26(22):5403-5410. doi: 10.1016/j.bmcl.2016.10.036. Epub 2016 Oct 14. PubMed PMID: 27780639.
Chemical Structure
