CVT-10216 is a Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50 values are 29 and 1300 nM for ALDH2 and ALDH1, respectively).
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Chemical Information
Name CVT-10216
Iupac Chemical Name 3-(((3-(4-(methylsulfonamido)phenyl)-4-oxo-4H-chromen-7-yl)oxy)methyl)benzoic acid
Synonyms CVT-10216; CVT 10216; CVT10216.
Molecular Formula C24H19NO7S
Molecular Weight 465.48
Smile CS(=O)(=O)NC1=CC=C(C=C1)C1=COC2=CC(=CC=C2C1=O)OCC=1C=C(C(=O)O)C=CC1
InChiKey YYOOFJZTRCPVFD-UHFFFAOYSA-N
InChi InChI=1S/C24H19NO7S/c1-33(29,30)25-18-7-5-16(6-8-18)21-14-32-22-12-19(9-10-20(22)23(21)26)31-13-15-3-2-4-17(11-15)24(27)28/h2-12,14,25H,13H2,1H3,(H,27,28)
CAS Number 1005334-57-5
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Ordering Information
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Formulation off-white solid
Purity 98.0%
Storage -20 ℃ for 3 years
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study