CX-5461
Catalog No: 52748
CAS Number: 1138549-36-6
Purity: 98%
CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation.
For research use only. We do not sell to patients.
Chemical Information
| Name | CX-5461 |
|---|---|
| Molecular Formula | C27H27N7O2S |
| Molecular Weight | 513.61 |
| Smile | Cc1cnc(cn1)CNC(=O)c2c(=O)c3ccc(nc3n4c2sc5c4cccc5)N6CCCN(CC6)C |
| InChiKey | XGPBJCHFROADCK-UHFFFAOYSA-N |
| InChi | InChI=1S/C27H27N7O2S/c1-17-14-29-18(15-28-17)16-30-26(36)23-24(35)19-8-9-22(33-11-5-10-32(2)12-13-33)31-25(19)34-20-6-3-4-7-21(20)37-27(23)34/h3-4,6-9,14-15H,5,10-13,16H2,1-2H3,(H,30,36) |
| CAS Number | 1138549-36-6 |
| MDL | MFCD21609261 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Solubility | DMSO <1.2mg/mL Water <1.2mg/mL Ethanol <1.2mg/mL |
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
