CZC24832 is a selective inhibitor of PI 3-kinase (IC50 = 1.0 M in a PI 3-K-dependent fMLP-induced neutrophil migration assay); exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other proteins.
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Name | CZC24832 |
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Molecular Formula | C15H17FN6O2S |
Molecular Weight | 364.4 |
Smile | CC(C)(C)NS(=O)(=O)c1cc(cnc1)c2cc(c3nc(nn3c2)N)F |
InChiKey | RXRZPHQBTHQXSV-UHFFFAOYSA-N |
InChi | InChI=1S/C15H17FN6O2S/c1-15(2,3)21-25(23,24)11-4-9(6-18-7-11)10-5-12(16)13-19-14(17)20-22(13)8-10/h4-8,21H,1-3H3,(H2,17,20) |
CAS Number | 1159824-67-5 |
MDL | MFCD22417090 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Purity | 98% |
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Solubility | DMSO |
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HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |