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Cabozantinib S-malate

Catalog No: 52778
CAS Number: 1140909-48-3
Purity: 98%

Cabozantinib S-malate (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4

For research use only. We do not sell to patients.

Chemical Information

NameCabozantinib S-malate
Molecular FormulaC32H30FN3O10
Molecular Weight635.59
SmileCOc1cc2c(ccnc2cc1OC)Oc3ccc(cc3)NC(=O)C4(CC4)C(=O)Nc5ccc(cc5)F.C([C@@H](C(=O)O)O)C(=O)O
InChiKeyHFCFMRYTXDINDK-WNQIDUERSA-N
InChiInChI=1S/C28H24FN3O5.C4H6O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18;5-2(4(8)9)1-3(6)7/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34);2,5H,1H2,(H,6,7)(H,8,9)/t;2-/m.0/s1
CAS Number1140909-48-3
MDLMFCD20923480
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Ordering Information

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Purity98%
SolubilityDMSO
Handling
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

52778 - Cabozantinib S-malate | CAS 1140909-48-3

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