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Camlipixant ( BLU-5937 )

Catalog No: 20455
CAS Number: 1621164-74-6
Purity: ≧98.0%

Camlipixant is an investigational, twice-daily oral P2X3 receptor antagonist for the treatment of RCC, which is currently being evaluated in the CALM phase III clinical development programme. Given the need for novel and effective medicines for RCC, camlipixant has the potential to be a breakthrough in the treatment landscape.

(RCC is a cough that persists for more than eight weeks despite optimal treatment of any underlying conditions or where there is no identifiable underlying cause. Cough hypersensitivity syndrome – excessive coughing, often in response to relatively innocuous stimuli – is now identified as the primary pathology in RCC. )

For research use only. We do not sell to patients.

Chemical Information

NameCamlipixant ( BLU-5937 )
Iupac Chemical Namemethyl (2S)-2-({2-[2,6-difluoro-4- (methylcarbamoyl)phenyl]-7-methylimidazo[1,2- a]pyridin-3-yl}methyl)morpholine-4-carboxylate
SynonymsCamlipixant ; BLU-5937 ; BLU5937 ; BLU 5937
Molecular FormulaC23H24F2N4O4
Molecular Weight458.46
SmileCC1=CC(N2C=C1)=NC(C3=C(F)C=C(C(NC)=O)C=C3F)=C2C[C@H]4CN(C(OC)=O)CCO4
InChiKeySEHLMRJSQFAPCJ-HNNXBMFYSA-N
InChiInChI=1S/C23H24F2N4O4/c1-13-4-5-29-18(11-15-12-28(6-7-33-15)23(31)32-3)21(27-19(29)8-13)20-16(24)9-14(10-17(20)25)22(30)26-2/h4-5,8-10,15H,6-7,11-12H2,1-3H3,(H,26,30)/t15-/m0/s1
CAS Number1621164-74-6
Related CAS1621164-74-6

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
Request Bulk Quote Download MSDS Tel : +86-177 0271 9238   Email : sales@sun-shinechem.com
FormulationOff-white solid
Purity≧98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
HandlingRefer to MSDS
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code2934200090
Coming soon.
TargetsP2X3 receptor antagonist
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

20455 - Camlipixant ( BLU-5937 ) | CAS 1621164-74-6

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