Cediranib
Catalog No: 52779
CAS Number: 288383-20-0
Purity:
Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/3 nM, similar activity against c-Kit and PDGFR, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-, CSF-1R and Flt3.
For research use only. We do not sell to patients.
Chemical Information
| Name | Cediranib |
|---|---|
| Molecular Formula | C25H27FN4O3 |
| Molecular Weight | 450.51 |
| Smile | Cc1cc2c([nH]1)ccc(c2F)Oc3c4cc(c(cc4ncn3)OCCCN5CCCC5)OC |
| InChiKey | XXJWYDDUDKYVKI-UHFFFAOYSA-N |
| InChi | InChI=1S/C25H27FN4O3/c1-16-12-17-19(29-16)6-7-21(24(17)26)33-25-18-13-22(31-2)23(14-20(18)27-15-28-25)32-11-5-10-30-8-3-4-9-30/h6-7,12-15,29H,3-5,8-11H2,1-2H3 |
| CAS Number | 288383-20-0 |
| MDL | MFCD09954115 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Handling | |
|---|---|
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
