Cevipabulin is a novel, potent, synthetic small molecule, inhibits binding of vinblastine at the Vinca alkaloid site of the _alpha__beta_-tubulin heterodimer.
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Chemical Information
Name Cevipabulin
Iupac Chemical Name 5-chloro-6-[2,6-difluoro-4-[3-(methylamino)propoxy]phenyl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
Synonyms UNII-P14M0DWS2J; Cevipabulin; TTI 237
Molecular Formula C18H18ClF5N6O
Molecular Weight 464.82
Smile ClC1=NC=2N(C(=C1C1=C(C=C(C=C1F)OCCCNC)F)N[C@H](C(F)(F)F)C)N=CN2
InChiKey ZUZPCOQWSYNWLU-VIFPVBQESA-N
InChi InChI=1S/C18H18ClF5N6O/c1-9(18(22,23)24)28-16-14(15(19)29-17-26-8-27-30(16)17)13-11(20)6-10(7-12(13)21)31-5-3-4-25-2/h6-9,25,28H,3-5H2,1-2H3/t9-/m0/s1
CAS Number 849550-05-6
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Ordering Information
Packaging Price Availability Purity Shipping Time
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Formulation Solid powder
Purity 98%
Storage -20 ºC for 3 years
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study