Cilofexor ( GS-9674 )
Catalog No: 19132
CAS Number: 1418274-28-8
Purity: ≧98.0%
Cilofexor (also known as GS-9674) is a nonsteroidal farnesoid X receptor (FXR) agonist in clinical trials for the treatment of non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH),and primary sclerosing cholangitis (PSC).
For research use only. We do not sell to patients.
Chemical Information
| Name | Cilofexor ( GS-9674 ) |
|---|---|
| Iupac Chemical Name | 2-(3-(2-chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)-3-hydroxyazetidin-1-yl)isonicotinic acid |
| Synonyms | Cilofexor; GS-9674; GS 9674; GS9674; |
| Molecular Formula | C28H22Cl3N3O5 |
| Molecular Weight | 586.85 |
| Smile | OC(C1=CC=NC(N2CC(O)(C2)C3=C(C=C(C=C3)OCC4=C(ON=C4C5=C(C=CC=C5Cl)Cl)C6CC6)Cl)=C1)=O |
| InChiKey | KZSKGLFYQAYZCO-UHFFFAOYSA-N |
| InChi | InChI=1S/C28H22Cl3N3O5/c29-20-2-1-3-21(30)24(20)25-18(26(39-33-25)15-4-5-15)12-38-17-6-7-19(22(31)11-17)28(37)13-34(14-28)23-10-16(27(35)36)8-9-32-23/h1-3,6-11,15,37H,4-5,12-14H2,(H,35,36) |
| CAS Number | 1418274-28-8 |
| Related CAS | 1418274-28-8 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS operation |
| Shipping Condition | Shipped under ambient temperature |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
