Cirtuvivint is a CDC-like kinase (CLK) and dual-specificity tyrosine-phosphorylation-regulated kinase (DYRK) inhibitors.
For research use only. We do not sell to patients.
Name | Cirtuvivint |
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Iupac Chemical Name | 2-(4-Methylpiperazin-1-yl)-N-[6-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-yl]pyridine-4-carboxamide |
Synonyms | Cirtuvivint ; SM08502 |
Molecular Formula | C24H25N7O |
Molecular Weight | 427.50 |
Smile | O=C(C1=CC(N2CCN(C)CC2)=NC=C1)NC3=CC4=C(C=N3)C=CC(C5=CN(C)N=C5)=C4 |
InChiKey | BQWWOBKMDWACGC-UHFFFAOYSA-N |
InChi | InChI=1S/C24H25N7O/c1-29-7-9-31(10-8-29)23-13-18(5-6-25-23)24(32)28-22-12-20-11-17(3-4-19(20)14-26-22)21-15-27-30(2)16-21/h3-6,11-16H,7-10H2,1-2H3,(H,26,28,32) |
CAS Number | 2143917-62-6 |
Related CAS | 2143917-62-6 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |
[1]. Betty Y Tam, et al. The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models. Cancer Lett. 2020 Mar 31;473:186-197.