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DCVC

Catalog No: 6111408
CAS Number: 13419-46-0
Purity: 98% 

DCVC inhibits pathogen-stimulated TNF- in human extra placental membranes in vitro.


DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 M) significantly inhibits LTA-, LPS-, and GBS-stimulated cytokine release from tissue cultures as early as 4 h (P 0.05). In contrast, TCA (up to 500 M) does not inhibit LTA-stimulated cytokine release from tissue punches. DCVC effects on LTA-stimulated and LPS-stimulated TNF- release from tissue punch cultures of extraplacental membranes. DCVC effects on GBS-stimulated release of pro-inflammatory cytokines from extraplacental membranes in transwell cultures.


 

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Chemical Information

NameDCVC
Iupac Chemical NameDCVC 
SynonymsS-[(1E)-1,2-dichloroethenyl]--L-cysteine 
Molecular FormulaC5H7Cl2NO2S 
Molecular Weight216.09 
SmileC([C@@H](C(=O)O)N)S/C(=C\Cl)/Cl
InChiKeyPJIHCWJOTSJIPQ-PEQLYWQKSA-N
InChiInChI=1S/C5H7Cl2NO2S/c6-1-4(7)11-2-3(8)5(9)10/h1,3H,2,8H2,(H,9,10)/b4-1-/t3-/m0/s1
CAS Number13419-46-0
MDLMFCD00870277
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Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

6111408 - DCVC | CAS 13419-46-0

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