DCVC inhibits pathogen-stimulated TNF- in human extra placental membranes in vitro.
DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 M) significantly inhibits LTA-, LPS-, and GBS-stimulated cytokine release from tissue cultures as early as 4 h (P 0.05). In contrast, TCA (up to 500 M) does not inhibit LTA-stimulated cytokine release from tissue punches. DCVC effects on LTA-stimulated and LPS-stimulated TNF- release from tissue punch cultures of extraplacental membranes. DCVC effects on GBS-stimulated release of pro-inflammatory cytokines from extraplacental membranes in transwell cultures.
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Name | DCVC |
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Iupac Chemical Name | DCVC |
Synonyms | S-[(1E)-1,2-dichloroethenyl]--L-cysteine |
Molecular Formula | C5H7Cl2NO2S |
Molecular Weight | 216.09 |
Smile | C([C@@H](C(=O)O)N)S/C(=C\Cl)/Cl |
InChiKey | PJIHCWJOTSJIPQ-PEQLYWQKSA-N |
InChi | InChI=1S/C5H7Cl2NO2S/c6-1-4(7)11-2-3(8)5(9)10/h1,3H,2,8H2,(H,9,10)/b4-1-/t3-/m0/s1 |
CAS Number | 13419-46-0 |
MDL | MFCD00870277 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | crystalline solid |
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Purity | 98% |
Storage | 3 years -20ºCpowder |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |