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DHPG

Catalog No: 25056
CAS Number: 146255-66-5
Purity: 98% Min.

DHPG, also known as (RS)-3,5-DHPG, is a selective agonist for group I metabotropic glutamate receptors (mGluRs), specifically targeting mGluR1 and mGluR5. Activation of these receptors by 3,5-DHPG has been shown to influence synaptic transmission and neuronal excitability. 3,5-DHPG, through its action on group I mGluRs, can modulate synaptic activity by promoting spontaneous neurotransmitter release in a patterned manner, which may have implications for understanding synaptic dynamics and developing therapeutic strategies targeting these receptors.

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Chemical Information

NameDHPG
Iupac Chemical Name2-amino-2-(3,5-dihydroxyphenyl)acetic acid
SynonymsDHPG; (RS)-3,5-DHPG
Molecular FormulaC8H9NO4
Molecular Weight183.16
SmileO=C(O)C(N)C1=CC(O)=CC(O)=C1
InChiKeyHOOWCUZPEFNHDT-UHFFFAOYSA-N
InChiInChI=1S/C8H9NO4/c9-7(8(12)13)4-1-5(10)3-6(11)2-4/h1-3,7,10-11H,9H2,(H,12,13)
CAS Number146255-66-5
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid
Purity98% Min.
StorageDry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

25056 - DHPG | CAS 146255-66-5

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