Dabrafenib
Catalog No: 52731
CAS Number: 1195765-45-7
Purity: 98%
Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively.
For research use only. We do not sell to patients.
Chemical Information
| Name | Dabrafenib |
|---|---|
| Molecular Formula | C23H20F3N5O2S2 |
| Molecular Weight | 519.56 |
| Smile | CC(C)(C)c1nc(c(s1)c2ccnc(n2)N)c3cccc(c3F)NS(=O)(=O)c4c(cccc4F)F |
| InChiKey | BFSMGDJOXZAERB-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H20F3N5O2S2/c1-23(2,3)21-30-18(19(34-21)16-10-11-28-22(27)29-16)12-6-4-9-15(17(12)26)31-35(32,33)20-13(24)7-5-8-14(20)25/h4-11,31H,1-3H3,(H2,27,28,29) |
| CAS Number | 1195765-45-7 |
| MDL | MFCD17215684 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Solubility | DMSO 48 mg/ml |
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
