Dabrafenib mesylate
Catalog No: 16122807
CAS Number: 1195768-06-9
Purity: 98%
Dabrafenib mesylate, also known as GSK 2118436B, is a potent and orally active B-raf (BRAF) inhibitor with in vitro IC50 values of 0.65, 0.5, and 1.84 nM for BRAF V600E, BRAF V600K, and BRAF V600D enzymes, respectively. Dabrafenib also inhibits wild-type
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Chemical Information
| Name | Dabrafenib mesylate |
|---|---|
| Iupac Chemical Name | Dabrafenib mesylate |
| Synonyms | GSK 2118436B; GSK2118436B; GSK-2118436B; GSK2118436 Methane sulfonate salt; Brand name: Taflinar. |
| Molecular Formula | C24H24F3N5O5S3 |
| Molecular Weight | 615.6612 |
| Smile | CC(C)(C)c1nc(c(s1)c2ccnc(n2)N)c3cccc(c3F)NS(=O)(=O)c4c(cccc4F)F.CS(=O)(=O)O |
| InChiKey | YKGMKSIHIVVYKY-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H20F3N5O2S2.CH4O3S/c1-23(2,3)21-30-18(19(34-21)16-10-11-28-22(27)29-16)12-6-4-9-15(17(12)26)31-35(32,33)20-13(24)7-5-8-14(20)25;1-5(2,3)4/h4-11,31H,1-3H3,(H2,27,28,29);1H3,(H,2,3,4) |
| CAS Number | 1195768-06-9 |
| MDL | MFCD20922872 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20℃powder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
