Debio 0932 ( CUDC-305 ) is a novel heat shock protein 90 (HSP90) inhibitor trong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L).
For research use only. We do not sell to patients.
Name | Debio 0932 |
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Iupac Chemical Name | Debio 0932 |
Synonyms | CUDC-305; Debio-0932; Debio0932; CUDC305; CUDC 305 |
Molecular Formula | C22H30N6O2S |
Molecular Weight | 442.58 |
Smile | CC(C)(C)CNCCn1c2ccnc(c2nc1Sc3cc4c(cc3N(C)C)OCO4)N |
InChiKey | RVJIQAYFTOPTKK-UHFFFAOYSA-N |
InChi | InChI=1S/C22H30N6O2S/c1-22(2,3)12-24-8-9-28-14-6-7-25-20(23)19(14)26-21(28)31-18-11-17-16(29-13-30-17)10-15(18)27(4)5/h6-7,10-11,24H,8-9,12-13H2,1-5H3,(H2,23,25) |
CAS Number | 1061318-81-7 |
MDL | MFCD18633209 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | crystalline solid |
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Purity | 98% |
Storage | 3 years -20ºCpowder |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |