Defactinib
Catalog No: 16122929
CAS Number: 1073160-26-5
Purity: 98%
Defactinib, also known as VS-6063 and PF04554878, is an orally bioavailable, small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. Defactinib inhibits FAK, which may prevent the integrin-mediated activation of several downstream signal transduction pathways, including those involving RAS/MEK/ERK and PI3K/Akt, thus inhibiting tumor cell migration, proliferation, survival, and tumor angiogenesis.
For research use only. We do not sell to patients.
Chemical Information
| Name | Defactinib |
|---|---|
| Iupac Chemical Name | 1073160-26-5 |
| Synonyms | Defactinib hydrochloride; Defactinib HCl; VS6063; VS 6063; VS-6063; PF04554878; PF-04554878; PF 04554878; PF4554878; PF-4554878; PF4554878 |
| Molecular Formula | C20H22ClF3N8O3S |
| Molecular Weight | 546.9542 |
| InChiKey | |
| InChi | |
| CAS Number | 1073160-26-5 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
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| Mechanism | |
| Cell study | |
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| Clinical study |
Not available
Chemical Structure
