Dimethylenastron
Catalog No: 16122932
CAS Number: 863774-58-7
Purity: 98%
Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5. The inhibition of kinesin Eg5 by small molecules such as monastrol is currently evaluated as an approach to develop a novel class of antiproliferative drugs for the treatment of malignant tumours.
For research use only. We do not sell to patients.
Chemical Information
| Name | Dimethylenastron |
|---|---|
| Iupac Chemical Name | Dimethylenastron |
| Synonyms | N/A |
| Molecular Formula | C16H18N2O2S |
| Molecular Weight | 302.392 |
| Smile | CC1(CC2=C(C(NC(=S)N2)c3cccc(c3)O)C(=O)C1)C |
| InChiKey | RUOOPLOUUAYNPY-UHFFFAOYSA-N |
| InChi | InChI=1S/C16H18N2O2S/c1-16(2)7-11-13(12(20)8-16)14(18-15(21)17-11)9-4-3-5-10(19)6-9/h3-6,14,19H,7-8H2,1-2H3,(H2,17,18,21) |
| CAS Number | 863774-58-7 |
| MDL | MFCD09264157 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
