Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 M, 9 M, respectively.
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Chemical Information
Name | Doxapram hydrochloride hydrate |
Iupac Chemical Name | 1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one;hydrate;hydrochloride |
Synonyms | Dopram hydrochloride hydrate; Stimulex hydrochloride hydrate; Respiram hydrochloride hydrate |
Molecular Formula | C24H33ClN2O3 |
Molecular Weight | 432.983 |
Smile | CCN1CC(C(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3)CCN4CCOCC4.O.Cl |
InChiKey | ZOMBFZRWMLIDPX-UHFFFAOYSA-N |
InChi | InChI=1S/C24H30N2O2.ClH.H2O/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21;;/h3-12,22H,2,13-19H2,1H3;1H;1H2 |
CAS Number | 7081-53-0 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | Solid powder |
Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |