E7449
Catalog No: 178903
CAS Number: 1140964-99-3
Purity: 98.0%
E7449 is an orally available small molecule inhibitor of the nuclear enzymes poly (ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | E7449 |
|---|---|
| Iupac Chemical Name | 8-(isoindolin-2-ylmethyl)-2H-pyridazino[3,4,5-de]quinazolin-3(9H)-one |
| Synonyms | E7449;E 7449;E-7449 |
| Molecular Formula | C18H15N5O |
| Molecular Weight | 317.34 |
| Smile | C1N(CC2=CC=CC=C12)CC1=NC=2C=CC=C3C2C(N1)=NNC3=O |
| InChiKey | JLFSBHQQXIAQEC-UHFFFAOYSA-N |
| InChi | InChI=1S/C18H15N5O/c24-18-13-6-3-7-14-16(13)17(21-22-18)20-15(19-14)10-23-8-11-4-1-2-5-12(11)9-23/h1-7H,8-10H2,(H,22,24)(H,19,20,21) |
| CAS Number | 1140964-99-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98.0% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
