EED226 is a potent, selective, and orally bioavailable EED inhibitor. induces robust and sustained tumor regression in EZH2MUT preclinical DLBCL model.
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Chemical Information
Name EED226
Iupac Chemical Name N-(Furan-2-ylmethyl)-8-(4-(methylsulfonyl)phenyl)[1,2,4]-triazolo[4,3-c]pyrimidin-5-amine
Synonyms EED226; EED-226; EED 226.
Molecular Formula C17H15N5O3S
Molecular Weight 369.399
Smile O1C(=CC=C1)CNC1=NC=C(C=2N1C=NN2)C2=CC=C(C=C2)S(=O)(=O)C
InChiKey DYIRSNMPIZZNBK-UHFFFAOYSA-N
InChi InChI=1S/C17H15N5O3S/c1-26(23,24)14-6-4-12(5-7-14)15-10-19-17(22-11-20-21-16(15)22)18-9-13-3-2-8-25-13/h2-8,10-11H,9H2,1H3,(H,18,19)
CAS Number 2083627-02-3
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Ordering Information
Packaging Price Availability Purity Shipping Time
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Formulation off-white solid
Purity 98.0%
Storage -20 ℃ for 3 years
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study