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EPZ015666

Catalog No: 011309
CAS Number: 1616391-65-1
Purity: 98% 

EPZ015666 is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki of 5 nM, >20,000-fold selectivity over other PMTs. 

For research use only. We do not sell to patients.

Chemical Information

NameEPZ015666
Iupac Chemical NameN-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide 
SynonymsEPZ-015666 
Molecular FormulaC20H25N5O3 
Molecular Weight383.44 
SmileC1CN(CC2=CC=CC=C21)CC(CNC(=O)C3=CC(=NC=N3)NC4COC4)O
InChiKeyZKXZLIFRWWKZRY-UHFFFAOYSA-N
InChiInChI=1S/C20H25N5O3/c26-17(10-25-6-5-14-3-1-2-4-15(14)9-25)8-21-20(27)18-7-19(23-13-22-18)24-16-11-28-12-16/h1-4,7,13,16-17,26H,5-6,8-12H2,(H,21,27)(H,22,23,24)
CAS Number1616391-65-1
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

011309 - EPZ015666 | CAS 1616391-65-1

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