Elvitegravir (EVG, formerly GS-9137) is an integrase inhibitor used to treat HIV infection.It was developed by the pharmaceutical company Gilead Sciences, which licensed EVG from Japan Tobacco in March 2008. The drug gained approval by the U.S. FDA on August 27, 2012 for use in adult patients starting HIV treatment for the first time as part of the fixed dose combination known as Stribild.
For research use only. We do not sell to patients.
Name | Elvitegravir(GS-9137) |
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Iupac Chemical Name | (S)-6-(3-chloro-2-fluorobenzyl)-1-(1-hydroxy-3-methylbutan-2-yl)-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
Synonyms | JTK-303 |
Molecular Formula | C23H23ClFNO5 |
Molecular Weight | 447.88 |
Smile | ClC=1C(=C(CC=2C=C3C(C(=CN(C3=CC2OC)[C@H](CO)C(C)C)C(=O)O)=O)C=CC1)F |
InChiKey | JUZYLCPPVHEVSV-LJQANCHMSA-N |
InChi | InChI=1S/C23H23ClFNO5/c1-12(2)19(11-27)26-10-16(23(29)30)22(28)15-8-14(20(31-3)9-18(15)26)7-13-5-4-6-17(24)21(13)25/h4-6,8-10,12,19,27H,7,11H2,1-3H3,(H,29,30)/t19-/m1/s1 |
CAS Number | 697761-98-1 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | off-white solid |
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Purity | 98% |
Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
Solubility | 5mg/ml in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
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Cell study | |
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Clinical study |