Entrectinib(RXDX-101)
Catalog No: 100504
CAS Number: 1108743-60-7
Purity: 98% by HPLC
Entrectinib (RXDX-101) is a selective inhibitor for all three TRK receptor tyrosine kinases encoded by the three NTRK genes, as well as the ROS1 and ALK receptor tyrosine kinases.
For research use only. We do not sell to patients.
Chemical Information
| Name | Entrectinib(RXDX-101) |
|---|---|
| Iupac Chemical Name | N-(5-(3,5-difluorobenzyl)-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-((tetrahydro-2H-pyran-4-yl)amino)benzamide |
| Synonyms | RXDX-101;RXDX 101;RXDX101;Entrectinib;NMS-E628 |
| Molecular Formula | C31H34F2N6O2 |
| Molecular Weight | 560.64 |
| Smile | O=C(NC1=NNC2=C1C=C(CC3=CC(F)=CC(F)=C3)C=C2)C4=CC=C(N5CCN(C)CC5)C=C4NC6CCOCC6 |
| InChiKey | HAYYBYPASCDWEQ-UHFFFAOYSA-N |
| InChi | InChI=1S/C31H34F2N6O2/c1-38-8-10-39(11-9-38)25-3-4-26(29(19-25)34-24-6-12-41-13-7-24)31(40)35-30-27-17-20(2-5-28(27)36-37-30)14-21-15-22(32)18-23(33)16-21/h2-5,15-19,24,34H,6-14H2,1H3,(H2,35,36,37,40) |
| CAS Number | 1108743-60-7 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% by HPLC |
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Solubility | Soluble in DMSO to 20 mM |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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