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Eprodisate Sodium

Catalog No: 16122940
CAS Number: 36589-58-9
Purity: 98% 

Eprodisate, also known as 3-PDS; NC-503; 3PDS, is an orally available disodium salt form of eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis. Upon administration, eprodisate competitively binds to the glycosaminoglycan binding sites on serum amyloid A (SAA), which inhibits the formation of the glycosaminoglycan-amyloid fibril aggregate. This prevents the formation of amyloid deposits in certain organs, especially the kidneys, in AA amyloidosis. 

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Chemical Information

NameEprodisate Sodium
Iupac Chemical NameEprodisate Sodium 
Synonyms3-PDS; NC-503; 3PDS; Eprodisate Sodium; Kiacta 
Molecular FormulaC3H6Na2O6S2 
Molecular Weight248.1745 
SmileC(CS(=O)(=O)[O-])CS(=O)(=O)[O-].[Na+].[Na+]
InChiKeyDKGJFKPIUSHDIT-UHFFFAOYSA-L
InChiInChI=1S/C3H8O6S2.2Na/c4-10(5,6)2-1-3-11(7,8)9;;/h1-3H2,(H,4,5,6)(H,7,8,9);;/q;2*+1/p-2
CAS Number36589-58-9
MDLMFCD00191483
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Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16122940 - Eprodisate Sodium | CAS 36589-58-9

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