F7H is a Frizzled receptor FZD7 antagonist.
For research use only. We do not sell to patients.
Name | F7H inhibitor |
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Iupac Chemical Name | 4-fluoro-N-(4-((2-oxo-2-((4-phenylthiazol-2-yl)amino)ethyl)thio)phenyl)benzamide |
Synonyms | F7H inhibitor; F7-H inhibitor; F-7H inhibitor; F-7-H inhibitor; F7-H; F-7H; F-7-H; F7H |
Molecular Formula | C24H18FN3O2S2 |
Molecular Weight | 463.55 |
Smile | O=C(C1=CC=C(C=C1)F)NC2=CC=C(C=C2)SCC(NC3=NC(C4=CC=CC=C4)=CS3)=O |
InChiKey | GEURGPJRAOYJKC-UHFFFAOYSA-N |
InChi | InChI=1S/C24H18FN3O2S2/c25-18-8-6-17(7-9-18)23(30)26-19-10-12-20(13-11-19)31-15-22(29)28-24-27-21(14-32-24)16-4-2-1-3-5-16/h1-14H,15H2,(H,26,30)(H,27,28,29) |
CAS Number | 897109-93-2 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | 98% Min. |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
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Clinical study |
1: Li C, Wu Y, Wang W, Xu L, Zhou Y, Yue Y, Wu T, Yang M, Qiu Y, Huang M, Zhou
F, Zhou Y, Hao P, Lin Z, Wang MW, Zhao S, Yang D, Xu F, Tao H. Structure-Based
Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7. J
Med Chem. 2023 Sep 14;66(17):11855-11868. doi: 10.1021/acs.jmedchem.2c01795.
Epub 2023 Sep 5. PMID: 37669317.
2: Diaba SY, Anafo T, Tetteh LA, Oyibo MA, Alola AA, Shafie-Khah M, Elmusrati M.
SCADA securing system using deep learning to prevent cyber infiltration. Neural
Netw. 2023 Aug;165:321-332. doi: 10.1016/j.neunet.2023.05.047. Epub 2023 Jun 2.
PMID: 37327579.