FPS-ZM1
Catalog No: 16123002
CAS Number: 945714-67-0
Purity: 98%
FPS-ZM1 is a high-affinity RAGE-specific blocker that inhibits amyloid- binding to RAGE, neurological damage and inflammation in the APP(sw/0) transgenic mouse model of AD. FPS-ZM1 is not toxic to mice and can easily cross the blood-brain barrier. AGEs administration induced an-regulation of Abeta production, inflammation, and oxidative stress, and an increased escape latency of rats in the Morris water maze test, all of these are significantly reduced by FPS-ZM1 treatment. FPS-ZM1 might be a novel therapeutic agent to treat AD patients.
For research use only. We do not sell to patients.
Chemical Information
| Name | FPS-ZM1 |
|---|---|
| Iupac Chemical Name | FPS-ZM1 |
| Synonyms | N/A |
| Molecular Formula | C20H22ClNO |
| Molecular Weight | 327.852 |
| Smile | C1C(C(N(C2CCCCC2)CC2C=CC=CC=2)=O)=CC=C(Cl)C=1 |
| InChiKey | XDFKWGIBQMHSOH-UHFFFAOYSA-N |
| InChi | InChI=1S/C20H22ClNO/c21-18-13-11-17(12-14-18)20(23)22(19-9-5-2-6-10-19)15-16-7-3-1-4-8-16/h1,3-4,7-8,11-14,19H,2,5-6,9-10,15H2 |
| CAS Number | 945714-67-0 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
