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FT113

Catalog No: 2071557
CAS Number: 1630808-89-7
Purity: 98% Min.

FT113 is a novel potent inhibitor of fatty acid synthase (fasn)

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Chemical Information

NameFT113
Iupac Chemical Name(4-(4-(6-Fluorobenzo[d]oxazol-2-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone
SynonymsFT113; FT 113; FT-113
Molecular FormulaC22H20FN3O4
Molecular Weight409.4174
SmileO=C(N1CCN(C(C2=CC=C(C3=NC4=CC=C(F)C=C4O3)C=C2)=O)CC1)C5(O)CC5
InChiKeyDSTWHRGOCUOKDE-UHFFFAOYSA-N
InChi InChI=1S/C22H20FN3O4/c23-16-5-6-17-18(13-16)30-19(24-17)14-1-3-15(4-2-14)20(27)25-9-11-26(12-10-25)21(28)22(29)7-8-22/h1-6,13,29H,7-12H2
CAS Number1630808-89-7
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder
Purity98% Min.
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study

1: Martin MW, Lancia DR Jr, Li H, Schiller SER, Toms AV, Wang Z, Bair KW, Castro J, Fessler S, Gotur D, Hubbs SE, Kauffman GS, Kershaw M, Luke GP, McKinnon C, Yao L, Lu W, Millan DS. Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN). Bioorg Med Chem Lett. 2019 Apr 15;29(8):1001-1006. doi: 10.1016/j.bmcl.2019.02.012. Epub 2019 Feb 11. PubMed PMID: 30803804.

Chemical Structure

2071557 - FT113 | CAS 1630808-89-7

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