FT113 is a novel potent inhibitor of fatty acid synthase (fasn)
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Name | FT113 |
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Iupac Chemical Name | (4-(4-(6-Fluorobenzo[d]oxazol-2-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone |
Synonyms | FT113; FT 113; FT-113 |
Molecular Formula | C22H20FN3O4 |
Molecular Weight | 409.4174 |
Smile | O=C(N1CCN(C(C2=CC=C(C3=NC4=CC=C(F)C=C4O3)C=C2)=O)CC1)C5(O)CC5 |
InChiKey | DSTWHRGOCUOKDE-UHFFFAOYSA-N |
InChi | InChI=1S/C22H20FN3O4/c23-16-5-6-17-18(13-16)30-19(24-17)14-1-3-15(4-2-14)20(27)25-9-11-26(12-10-25)21(28)22(29)7-8-22/h1-6,13,29H,7-12H2 |
CAS Number | 1630808-89-7 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | Solid powder |
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Purity | 98% Min. |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
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Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
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1: Martin MW, Lancia DR Jr, Li H, Schiller SER, Toms AV, Wang Z, Bair KW, Castro J, Fessler S, Gotur D, Hubbs SE, Kauffman GS, Kershaw M, Luke GP, McKinnon C, Yao L, Lu W, Millan DS. Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN). Bioorg Med Chem Lett. 2019 Apr 15;29(8):1001-1006. doi: 10.1016/j.bmcl.2019.02.012. Epub 2019 Feb 11. PubMed PMID: 30803804.