GCN2iB
Catalog No: 2071802
CAS Number: 2183470-12-2
Purity: 98%
GCN2iB is an ATP-competitive GCN2 inhibitory compound with a better pharmacokinetic profile. GCN2iB showed an IC50 value of 2.4 nmol/L for GCN2 and potent cellular activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | GCN2iB |
|---|---|
| Iupac Chemical Name | N-[3-[2-(2-Amino-5-pyrimidinyl)ethynyl]-2,4-difluorophenyl]-5-chloro-2-methoxy- 3-pyridinesulfonamide |
| Synonyms | GCN2iB |
| Molecular Formula | C₁₈H₁₂ClF₂N₅O₃S |
| Molecular Weight | 451.83 |
| Smile | O=S(C1=CC(Cl)=CN=C1OC)(NC2=CC=C(F)C(C#CC3=CN=C(N)N=C3)=C2F)=O |
| InChiKey | JGHVXJKGYJYWOP-UHFFFAOYSA-N |
| InChi | InChI=1S/C18H12ClF2N5O3S/c1-29-17-15(6-11(19)9-23-17)30(27,28)26-14-5-4-13(20)12(16(14)21)3-2-10-7-24-18(22)25-8-10/h4-9,26H,1H3,(H2,22,24,25) |
| CAS Number | 2183470-12-2 |
| Related CAS | 2183470-12-2 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2933599090 |
| Targets | GCN2 inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
