GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR.
For research use only. We do not sell to patients.
Name | GDC-0349 |
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Iupac Chemical Name | (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea |
Synonyms | GDC0349,GDC 0349 |
Molecular Formula | C24H32N6O3 |
Molecular Weight | 452.55 |
Smile | C(C)NC(=O)NC1=CC=C(C=C1)C=1N=C(C2=C(N1)CN(CC2)C2COC2)N2[C@H](COCC2)C |
InChiKey | RGJOJUGRHPQXGF-INIZCTEOSA-N |
InChi | InChI=1S/C24H32N6O3/c1-3-25-24(31)26-18-6-4-17(5-7-18)22-27-21-12-29(19-14-33-15-19)9-8-20(21)23(28-22)30-10-11-32-13-16(30)2/h4-7,16,19H,3,8-15H2,1-2H3,(H2,25,26,31)/t16-/m0/s1 |
CAS Number | 1207360-89-1 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | crystalline solid |
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Purity | >98% by HPLC |
Storage | 3 years -20ºCpowder |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |