GDC-0810 ( Brilanestrant , ARN-810 )
Catalog No: 90731
CAS Number: 1365888-06-7
Purity: ≧98.0%
GDC-0810 (Brilanestrant, ARN-810, RG6046) is a selective estrogen receptor degrader (SERD) that is designed to bind to the estrogen receptor to limit its function. In addition, when SERDs bind to the estrogen receptor, they may be able to change the shape of the receptor in such a way that the cell eliminates it by degradation.
For research use only. We do not sell to patients.
Chemical Information
| Name | GDC-0810 ( Brilanestrant , ARN-810 ) |
|---|---|
| Iupac Chemical Name | (E)-3-(4-((E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-en-1-yl)phenyl)acrylic acid |
| Synonyms | Brilanestrant ; GDC-0810 ; GDC 0810 ; GDC0810 ; ARN-810 ; ARN 810 ; ARN810 |
| Molecular Formula | C26H20ClFN2O2 |
| Molecular Weight | 446.90 |
| Smile | O=C(O)/C=C/C1=CC=C(/C(C2=CC3=C(NN=C3)C=C2)=C(C4=CC=C(F)C=C4Cl)/CC)C=C1 |
| InChiKey | BURHGPHDEVGCEZ-KJGLQBJMSA-N |
| InChi | InChI=1S/C26H20ClFN2O2/c1-2-21(22-10-9-20(28)14-23(22)27)26(18-8-11-24-19(13-18)15-29-30-24)17-6-3-16(4-7-17)5-12-25(31)32/h3-15H,2H2,1H3,(H,29,30)(H,31,32)/b12-5+,26-21+ |
| CAS Number | 1365888-06-7 |
| Related CAS | 1365888-06-7 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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