GDC-0927, also known as SRN-927, is a next-generation oral SERD which appears to have greater potential than GDC-0810 to be a best-in-class SERD molecule.
For research use only. We do not sell to patients.
Name | GDC-0927 |
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Iupac Chemical Name | (2S)-2-(4-{2-[3-(Fluoromethyl)-1-azetidinyl]ethoxy}phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-chromen-6-ol |
Synonyms | GDC-0927; GDC 0927; GDC0927; SRN-927; SRN 927; SRN927. |
Molecular Formula | C28H28FNO4 |
Molecular Weight | 461.53 |
Smile | OC1=CC(C(C)=C(C2=CC=CC(O)=C2)[C@H](C3=CC=C(OCCN4CC(CF)C4)C=C3)O5)=C5C=C1 |
InChiKey | KJAAPZIFCQQQKX-NDEPHWFRSA-N |
InChi | InChI=1S/C28H28FNO4/c1-18-25-14-23(32)7-10-26(25)34-28(27(18)21-3-2-4-22(31)13-21)20-5-8-24(9-6-20)33-12-11-30-16-19(15-29)17-30/h2-10,13-14,19,28,31-32H,11-12,15-17H2,1H3/t28-/m0/s1 |
CAS Number | 1642297-01-5 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
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Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |