GNE-6640 is a novel selective USP7 inhibitor, inducing tumor cell death. GNE-6640 enhances cytotoxicity with chemotherapeutic agents and targeted compounds, including PIM kinase inhibitors.
For research use only. We do not sell to patients.
Name | GNE-6640 |
---|---|
Iupac Chemical Name | 4-[2-Amino-4-ethyl-5-(1H-indazol-5-yl)-3-pyridyl]phenol |
Synonyms | GNE-6640; GNE 6640; GNE6640 |
Molecular Formula | C20H18N4O |
Molecular Weight | 330.39 |
Smile | OC1=CC=C(C2=C(CC)C(C3=CC4=C(NN=C4)C=C3)=CN=C2N)C=C1 |
InChiKey | ZHYXJQQBKROZDX-UHFFFAOYSA-N |
InChi | InChI=1S/C20H18N4O/c1-2-16-17(13-5-8-18-14(9-13)10-23-24-18)11-22-20(21)19(16)12-3-6-15(25)7-4-12/h3-11,25H,2H2,1H3,(H2,21,22)(H,23,24) |
CAS Number | 2009273-67-8 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
---|---|---|---|---|
Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
---|---|
Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
---|---|
Mechanism | |
Cell study | |
Animal study | |
Clinical study |