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GRA Ex-25

Catalog No: 17030701
CAS Number: 307983-31-9
Purity: 98% 

GRA Ex-25 is an inhibitor of glucagon receptor. Inhibiting the interaction between glucagon and its receptor has been reported to control hepatic glucose overproduction and thus GCGR has evolved as an attractive therapeutic target for the treatment of type II diabetes mellitus. 

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Chemical Information

NameGRA Ex-25
Iupac Chemical Name3-(4-((1-(4-(tert-butyl)cyclohexyl)-3-(4-(trifluoromethoxy)phenyl)ureido)methyl)benzamido)propanoic acid 
SynonymsGRA Ex-25; GRA Ex 25; GRA Ex25; GRAEx-25; GRAEx 25; GRAEx25 
Molecular FormulaC29H36F3N3O5 
Molecular Weight563.6182 
SmileC(C)(C)(C)C1CCC(CC1)N(C(=O)NC1=CC=C(C=C1)OC(F)(F)F)CC1=CC=C(C(=O)NCCC(=O)O)C=C1
InChiKeyBZXMLCVDKDXRQY-UHFFFAOYSA-N
InChiInChI=1S/C29H36F3N3O5/c1-28(2,3)21-8-12-23(13-9-21)35(27(39)34-22-10-14-24(15-11-22)40-29(30,31)32)18-19-4-6-20(7-5-19)26(38)33-17-16-25(36)37/h4-7,10-11,14-15,21,23H,8-9,12-13,16-18H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)
CAS Number307983-31-9
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Ordering Information

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Formulationoff-white solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

17030701 - GRA Ex-25 | CAS 307983-31-9

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