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GSK-591

Catalog No: 6111009
CAS Number: 1616391-87-7
Purity: 98% 

EPZ015866 (GSK591) is a potent selective inhibitor of the arginine methyltransferase PRMT5. It maintained excellent selectivity against other PMT enzymes observed with EPZ015666 

For research use only. We do not sell to patients.

Chemical Information

NameGSK-591
Iupac Chemical NameGSK-591 
SynonymsGSK591, GSK-591, GSK 591, EPZ 015866, EPZ-015866, GSK 3203591, GSK-3203591, GSK3203591 
Molecular FormulaC22H28N4O2 
Molecular Weight380.22 
SmileC1(CCC1)NC1=NC=CC(=C1)C(=O)NC[C@@H](CN1CC2=CC=CC=C2CC1)O
InChiKeyTWKYXZSXXXKKJU-FQEVSTJZSA-N
InChiInChI=1S/C22H28N4O2/c27-20(15-26-11-9-16-4-1-2-5-18(16)14-26)13-24-22(28)17-8-10-23-21(12-17)25-19-6-3-7-19/h1-2,4-5,8,10,12,19-20,27H,3,6-7,9,11,13-15H2,(H,23,25)(H,24,28)/t20-/m0/s1
CAS Number1616391-87-7
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Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

6111009 - GSK-591 | CAS 1616391-87-7

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