GSK583
Catalog No: 16123014
CAS Number: 1346547-00-9
Purity: 98%
GSK583 is a Highly Potent and Selective Inhibitor of RIP2 Kinase (RIP2K bing IC50=5 nM; rat in vivo PD IC50 = 50 nM). RIP2 kinase is a central component of the innate immune system and enables downstream signaling following activation of the pattern recognition receptors NOD1 and NOD2, leading to the production of inflammatory cytokines.
For research use only. We do not sell to patients.
Chemical Information
| Name | GSK583 |
|---|---|
| Iupac Chemical Name | GSK583 |
| Synonyms | GSK 583; GSK-583 |
| Molecular Formula | C20H19FN4O2S |
| Molecular Weight | 398.4564 |
| InChiKey | |
| InChi | |
| CAS Number | 1346547-00-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
