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GTS-21

Catalog No: 16123016
CAS Number: 156223-05-1
Purity: 98% 

GTS-21, also known as DMBX-A, is a derivative of the natural product anabaseine that acts as a partial agonist at neural nicotinic acetylcholine receptors. It binds to both the 42 and 7 subtypes, but activates only the 7 to any significant extent. Both GTS-21 itself and its demethylated active metabolite 4-OH-GTS-21 display nootropic[4] and neuroprotective effects, and GTS-21 is being investigated for the treatment of Alzheimer's disease, nicotine dependence,[10] and, most significantly, for schizophrenia. (https://en.wikipedia.org/wiki/GTS-21). 

For research use only. We do not sell to patients.

Chemical Information

NameGTS-21
Iupac Chemical NameGTS-21 
SynonymsGTS 21; GTS21; DMBX-A 
Molecular FormulaC19H20N2O2 
Molecular Weight308.381 
SmileCOc1ccc(c(c1)OC)/C=C/2\CCCN=C2c3cccnc3.Cl.Cl
InChiKeyBXKYFUGAAFLYJL-BXGYHSFXSA-N
InChiInChI=1S/C19H20N2O2.2ClH/c1-22-17-8-7-14(18(12-17)23-2)11-15-5-4-10-21-19(15)16-6-3-9-20-13-16;;/h3,6-9,11-13H,4-5,10H2,1-2H3;2*1H/b15-11+;;
CAS Number156223-05-1
MDLMFCD00941364
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Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16123016 - GTS-21 | CAS 156223-05-1

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