GT 949 is a selective EAAT2 positive allosteric modulator (EC50 = 0.26 nM). Enhances the glutamate translocation rate, with no effect on substrate interaction.
For research use only. We do not sell to patients.
Name | GT 949 |
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Iupac Chemical Name | 3-((4-Cyclohexylpiperazin-1-yl)(1-phenethyl-1H-tetrazol-5-yl)methyl)-6-methoxyquinolin-2(1H)-one |
Synonyms | GT 949 |
Molecular Formula | C30H37N7O2 |
Molecular Weight | 527.66 |
Smile | COC1=CC=C2NC(C(C(C3=NN=NN3CCC4=CC=CC=C4)N5CCN(C6CCCCC6)CC5)=CC2=C1)=O |
InChiKey | ZVWPOIUAPXDLMB-UHFFFAOYSA-N |
InChi | |
CAS Number | 460330-27-2 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
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Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |