GW-280264 ( GW-280264X ) is the mixed ADAM10/TACE (ADAM17) metalloproteinases inhibitor.
For research use only. We do not sell to patients.
Name | GW-280264 ( GW-280264X ) |
---|---|
Iupac Chemical Name | N6-(Benzyloxycarbonyl)-N2-[3(S)-(N-formyl-N-hydroxyamino)-2(R)-isobutylhexanoyl]-N1-(2-thiazolyl)-L-lysinamide |
Synonyms | GW-280264 ; GW-280264X ; GW280264 ; GW280264X ; GW 280264 ; GW 280264X |
Molecular Formula | C28H41N5O6S |
Molecular Weight | 575.72 |
Smile | O=C(OCC1=CC=CC=C1)NCCCC[C@H](NC([C@H](CC(C)C)[C@@H](N(C=O)O)CCC)=O)C(NC2=NC=CS2)=O |
InChiKey | SKJLITFHSZNZMQ-SGNDLWITSA-N |
InChi | InChI=1S/C28H41N5O6S/c1-4-10-24(33(38)19-34)22(17-20(2)3)25(35)31-23(26(36)32-27-29-15-16-40-27)13-8-9-14-30-28(37)39-18-21-11-6-5-7-12-21/h5-7,11-12,15-16,19-20,22-24,38H,4,8-10,13-14,17-18H2,1-3H3,(H,30,37)(H,31,35)(H,29,32,36)/t22-,23+,24+/m1/s1 |
CAS Number | 866924-39-2 |
Related CAS | 866924-39-2 |
Packaging | Price | Availability | Purity | Shipping Time |
---|---|---|---|---|
Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
---|---|
Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | ADAM10/TACE (ADAM17) metalloproteinases inhibitor. |
---|---|
Mechanism | Disintegrin and Metalloproteinase Domain-Containing Protein 10 (ADAM10) Inhibitors |
Cell study | Signal Transduction Modulators |
Animal study | |
Clinical study | Biological Testing |