GW2580 is an orally bioavailable inhibitor of c-FMS kinase; completely inhibited human cFMS kinase in vitro at 0.06 microM and was inactive against 26 other kinases.
For research use only. We do not sell to patients.
Name | GW2580 |
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Iupac Chemical Name | 5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine |
Synonyms | GW-2580 ; GW2580 ; GW 2580 |
Molecular Formula | C20H22N4O3 |
Molecular Weight | 366.414 |
Smile | COC1=CC=C(C=C1)COC2=C(C=C(C=C2)CC3=CN=C(N=C3N)N)OC |
InChiKey | MYQAUKPBNJWPIE-UHFFFAOYSA-N |
InChi | InChI=1S/C20H22N4O3/c1-25-16-6-3-13(4-7-16)12-27-17-8-5-14(10-18(17)26-2)9-15-11-23-20(22)24-19(15)21/h3-8,10-11H,9,12H2,1-2H3,(H4,21,22,23,24) |
CAS Number | 870483-87-7 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | Off-white solid to white solid |
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Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
Shipping Condition | Shipped under ambient temperature |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |