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GW788388

Catalog No: 52305
CAS Number: 452342-67-5
Purity: 98% 

GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, also inhibits TGF- type II receptor and activin type II receptor activities, but does not inhibit BMP type II receptor. 

For research use only. We do not sell to patients.

Chemical Information

NameGW788388
Iupac Chemical Name4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide 
SynonymsGW788388;GW-788388 
Molecular FormulaC25H23N5O2 
Molecular Weight425.48 
SmileO=C(NC1CCOCC1)C2=CC=C(C3=NC=CC(C4=CNN=C4C5=NC=CC=C5)=C3)C=C2
InChiKeySAGZIBJAQGBRQA-UHFFFAOYSA-N
InChiInChI=1S/C25H23N5O2/c31-25(29-20-9-13-32-14-10-20)18-6-4-17(5-7-18)23-15-19(8-12-27-23)21-16-28-30-24(21)22-3-1-2-11-26-22/h1-8,11-12,15-16,20H,9-10,13-14H2,(H,28,30)(H,29,31)
CAS Number452342-67-5
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Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
Solubility2mg/ml in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

52305 - GW788388 | CAS 452342-67-5

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