GW9662 is a selective PPAR antagonist for PPAR with IC50 of 3.3 nM, with at least 100 to 1000-fold functional selectivity in cells with PPAR versus PPAR and PPAR.
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Chemical Information
Name GW9662
Iupac Chemical Name Benzamide, 2-chloro-5-nitro-N-phenyl-
Synonyms N/A
Molecular Formula C13H9ClN2O3
Molecular Weight 276.68
Smile O=C(NC1=CC=CC=C1)C2=CC([N+]([O-])=O)=CC=C2Cl
InChiKey DNTSIBUQMRRYIU-UHFFFAOYSA-N
InChi InChI=1S/C13H9ClN2O3/c14-12-7-6-10(16(18)19)8-11(12)13(17)15-9-4-2-1-3-5-9/h1-8H,(H,15,17)
CAS Number 22978-25-2
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Ordering Information
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Formulation crystalline solid
Purity 98%
Storage 3 years -20ºCpowder 6 months-80ºCin solvent
Solubility 2mg/ml in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study