Golidocitinib (AZD-4205) is an oral JAK1 selective kinase inhibitor.
For research use only. We do not sell to patients.
Name | Golidocitinib ( AZD-4205 ) |
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Iupac Chemical Name | (2R)-N-(3-[2-[(3-Methoxy-1-methyl-1H-pyrazol-4-yl)amino]pyrimidin-4-yl]-1H-indol-7-yl)-2-(4-methylpiperazin-1-yl)propanamide |
Synonyms | AZD4205 ;Golidocitinib ; AZD-4205 ; AZD 4205 |
Molecular Formula | C25H31N9O2 |
Molecular Weight | 489.57 |
Smile | C[C@@H](N1CCN(C)CC1)C(NC2=C3C(C(C4=NC(NC5=CN(C)N=C5OC)=NC=C4)=CN3)=CC=C2)=O |
InChiKey | CVCVOSPZEVINRM-MRXNPFEDSA-N |
InChi | InChI=1S/C25H31N9O2/c1-16(34-12-10-32(2)11-13-34)23(35)28-20-7-5-6-17-18(14-27-22(17)20)19-8-9-26-25(29-19)30-21-15-33(3)31-24(21)36-4/h5-9,14-16,27H,10-13H2,1-4H3,(H,28,35)(H,26,29,30)/t16-/m1/s1 |
CAS Number | 2091134-68-6 |
Related CAS | 2091134-68-6 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Light yellow to yellow (Solid) |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |