HMPL-523
Catalog No: 20123101
CAS Number: 1415792-84-5
Purity: ≧98.0%
HMPL-523 is a novel, highly selective and potent small molecule oral inhibitor targeting spleen tyrosine kinase, also known as Syk, a key component in B-cell receptor signaling.
For research use only. We do not sell to patients.
Chemical Information
| Name | HMPL-523 |
|---|---|
| Iupac Chemical Name | (S)-7-(4-(1-(methylsulfonyl)piperidin-4-yl)phenyl)-N-(morpholin-2-ylmethyl)pyrido[3,4-b]pyrazin-5-amine |
| Synonyms | HMPL-523 ; HMPL523 ; HMPL 523 |
| Molecular Formula | C24H30N6O3S |
| Molecular Weight | 482.5984 |
| Smile | O=S(N1CCC(C2=CC=C(C3=NC(NC[C@@H]4CNCCO4)=C(N=CC=N5)C5=C3)C=C2)CC1)(C)=O |
| InChiKey | NJIAKNWTIVDSDA-FQEVSTJZSA-N |
| InChi | InChI=1S/C24H30N6O3S/c1-34(31,32)30-11-6-18(7-12-30)17-2-4-19(5-3-17)21-14-22-23(27-9-8-26-22)24(29-21)28-16-20-15-25-10-13-33-20/h2-5,8-9,14,18,20,25H,6-7,10-13,15-16H2,1H3,(H,28,29)/t20-/m0/s1 |
| CAS Number | 1415792-84-5 |
| Related CAS | 1415792-84-5 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2933999701 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
