NVP-HSP990 (HSP990) is a novel, potent and selective HSP90 inhibitor for HSP90/ with IC50 of 0.6 nM/0.8 nM.
For research use only. We do not sell to patients.
Name | HSP990 (NVP-HSP990) |
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Iupac Chemical Name | (7R)-2-amino-7-[4-fluoro-2-(6-methoxy-2-pyridinyl)phenyl]-7,8-dihydro-4-methyl-pyrido[4,3-d]pyrimidin-5(6H)-one |
Synonyms | NVP-HSP990,HSP990 |
Molecular Formula | C20H18FN5O2 |
Molecular Weight | 379.39 |
Smile | NC=1N=C(C2=C(N1)C[C@@H](NC2=O)C2=C(C=C(C=C2)F)C2=NC(=CC=C2)OC)C |
InChiKey | WSMQUUGTQYPVPD-OAHLLOKOSA-N |
InChi | InChI=1S/C20H18FN5O2/c1-10-18-16(26-20(22)23-10)9-15(25-19(18)27)12-7-6-11(21)8-13(12)14-4-3-5-17(24-14)28-2/h3-8,15H,9H2,1-2H3,(H,25,27)(H2,22,23,26)/t15-/m1/s1 |
CAS Number | 934343-74-5 |
Related CAS |
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Formulation | off-white solid |
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Purity | 98% |
Storage | 3 years -20ºCpowder |
Solubility | 5mg/ml in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |