IACS-13909 is a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway.
For research use only. We do not sell to patients.
Name | IACS-13909 |
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Iupac Chemical Name | 1-[3-(2,3-Dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl-4-piperidinamine |
Synonyms | IACS 13909 ; IACS-13909 ; IACS13909 ; |
Molecular Formula | C17H18Cl2N6 |
Molecular Weight | 377.27 |
Smile | NC1(C)CCN(C2=CN=C3C(NN=C3C4=CC=CC(Cl)=C4Cl)=N2)CC1 |
InChiKey | AMADCPJVPLUGQO-UHFFFAOYSA-N |
InChi | InChI=1S/C17H18Cl2N6/c1-17(20)5-7-25(8-6-17)12-9-21-15-14(23-24-16(15)22-12)10-3-2-4-11(18)13(10)19/h2-4,9H,5-8,20H2,1H3,(H,22,23,24) |
CAS Number | 2160546-07-4 |
Related CAS | 2160546-07-4 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white to light-yellow solid |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |