Highly selective 2 adrenoceptor antagonist (Ki values are 1.2, 120 and 257 nM at 2 , 1 and 3 receptors, respectively). Blood-brain barrier permeable. Decreases vascular tone in vivo .
For research use only. We do not sell to patients.
Chemical Information
Name ICI118551(HCl)
Iupac Chemical Name (2R*,3R*)-1-[(2,3-Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol
Synonyms ICI 118551 hydrochloride;ICI-118551 hydrochloride;ICI118551 hydrochloride
Molecular Formula C17H27NO2.HCl
Molecular Weight 313.87
Smile C[C@@H](NC(C)C)[C@@H](O)COC1=CC=C(C)C2=C1CCC2
InChiKey VFIDUCMKNJIJTO-CJNGLKHVSA-N
InChi InChI=1S/C17H27NO2/c1-11(2)18-13(4)16(19)10-20-17-9-8-12(3)14-6-5-7-15(14)17/h8-9,11,13,16,18-19H,5-7,10H2,1-4H3/t13-,16+/m1/s1
CAS Number 72795-01-8
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Ordering Information
Packaging Price Availability Purity Shipping Time
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Formulation off-white solid
Purity 98%
Storage 3 years -20ºCpowder
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature as non-hazardous chemical.
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study