INCB057643

Catalog No: 185232

CAS Number: 1820889-23-3

Purity: >98%

INCB057643 is a BET inhibitor. INCB054329 reduces homologous recombination efficiency and augments PARP inhibitor activity in ovarian cancer.

For research use only. We do not sell to patients.

Name	INCB057643
Iupac Chemical Name	2,2,4-trimethyl-8-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-6-(methylsulfonyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Synonyms	INCB057643; INCB-057643; INCB 057643;
Molecular Formula	C20H21N3O5S
Molecular Weight	415.464
Smile	CN(C(C(C)(C)O1)=O)C2=C1C(C(C3=C4NC=C3)=CN(C)C4=O)=CC(S(C)(=O)=O)=C2
InChiKey	VZSAMEOETVNDQH-UHFFFAOYSA-N
InChi	InChI=1S/C20H21N3O5S/c1-20(2)19(25)23(4)15-9-11(29(5,26)27)8-13(17(15)28-20)14-10-22(3)18(24)16-12(14)6-7-21-16/h6-10,21H,1-5H3
CAS Number	1820889-23-3
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Formulation	Off-white solid to white solid
Purity	>98%
Storage	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility	Soluble in DMSO
Handling
Shipping Condition	Shipped under ambient temperature
HS Code

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