INCB3344
Catalog No: 185215
CAS Number: 1262238-11-8
Purity: >98%
INCB3344 is a potent and selective antagonist of CCR2 receptor with IC(50) values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | INCB3344 |
|---|---|
| Iupac Chemical Name | N-(2-(((3S,4S)-1-(4-(benzo[d][1,3]dioxol-5-yl)-4-hydroxycyclohexyl)-4-ethoxypyrrolidin-3-yl)amino)-2-oxoethyl)-3-(trifluoromethyl)benzamide |
| Synonyms | INCB3344; INCB-3344; INCB 3344. |
| Molecular Formula | C29H34F3N3O6 |
| Molecular Weight | 577.6012 |
| Smile | O=C(NCC(N[C@H]1CN(C2CCC(O)(C3=CC=C(OCO4)C4=C3)CC2)C[C@@H]1OCC)=O)C5=CC=CC(C(F)(F)F)=C5 |
| InChiKey | MZEOSVPWMSEFPW-XYCDVDSTSA-N |
| InChi | InChI=1S/C29H34F3N3O6/c1-2-39-25-16-35(21-8-10-28(38,11-9-21)19-6-7-23-24(13-19)41-17-40-23)15-22(25)34-26(36)14-33-27(37)18-4-3-5-20(12-18)29(30,31)32/h3-7,12-13,21-22,25,38H,2,8-11,14-17H2,1H3,(H,33,37)(H,34,36)/t21?,22-,25-,28?/m0/s1 |
| CAS Number | 1262238-11-8 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | >98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
